0
ARTICLE |

A New Preparation for Study of the Completely Isolated Mammalian Heart and Lungs

ROBERT ALLANSMITH, M.D.; CARLETON W. MATHEWSON, M.D.
AMA Arch Surg. 1960;80(5):822-829. doi:10.1001/archsurg.1960.01290220114013.
Text Size: A A A
Published online

Much of the basic experimental work which made the recent advances in the treatment of heart disease possible was done on one or another of the various preparations for isolating the heart and lungs. The study of any individual organ is facilitated by its isolation from the other organs in the body. In the investigation of the heart, it was found that the mammalian heart did not lend itself to isolation as did the heart of the frog and the turtle.

The problem of getting the isolated mammalian heart to perform work pumping blood and not just to beat has intrigued many prominent physiologists. Although the heart continues to beat as long as its coronary arteries are perfused, its energetics, metabolism, and other vital functions cannot be evaluated unless it is performing work. The qualitative and quantitative analysis of undiluted coronary blood is difficult because the collection of such blood

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();