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May 1960, Vol 80, No. 5 >
ARTICLE | May 1960

Successful Treatment of Portal Vein Thrombosis Associated with Intrahepatic Obstruction

WILLIAM S. DYE, M.D.; DOUGLAS DAVID, M.D.; ORMAND C. JULIAN, M.D., Ph.D.
AMA Arch Surg. 1960;80(5):876-882. doi:10.1001/archsurg.1960.01290220168021.
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Portal thrombosis may be associated with cirrhosis of the liver. It may alter the course of the disease and be responsible for deterioration in many cases. This complication has been emphasized by Liebowitz3 and many others. The purpose of this paper is to reemphasize this problem and report surgical removal of the thrombus in six cases at the time of exploration for possible portacaval shunt. Also our experience with hepatic vein catheterization and its relation to this problem will be outlined.

Hunt,1 in 1954, recorded the histories of seven patients with cirrhosis and stated that 11% of the cirrhotic patients had actual thrombosis of the portal vein. He reported that treatment with heparin in certain cases had been successful. He removed a thrombus successfully in three cases and completed a portacaval shunt. Linton4 has also reported removing a partially organized thrombus from the portal vein. Walker14

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