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ARTICLE | November 1960

Progressive Malignant Degeneration of a Cystadenoma of the Pancreas

J. G. PROBSTEIN, M.D.; HERMAN T. BLUMENTHAL, M.D.

Arch Surg. 1960;81(5):683-689. doi:10.1001/archsurg.1960.01300050005002.

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It would appear from the surgical literature that benign cystadenoma of the pancreas is a rare lesion. Thus through 1954, according to Zintel et al.,²⁴ there were only 58 such cases reported. In the same year Trapnell²¹ also reported a case and stated that he could discover only 2 cases reported as occurring in England and only 1 in Ireland. He also cited case reports by Haukohl and Melamed⁹ and one by Tagariello²⁰ not included in previous reviews. In 1956, Glenner and Mallory⁷ presented a comprehensive study of tumors of the pancreas including cystadenoma, but gave no additional information as to its frequency.

According to Kennard¹⁰ malignant degeneration of a benign cystadenoma of the pancreas is rare. The cases reported by Lichenstein,¹¹ Maes,¹² and by Carter and Slattery⁵ indicate that benign cystadenoma of the pancreas may assume malignant characteristics, but this

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PROBSTEIN JG, BLUMENTHAL HT. Progressive Malignant Degeneration of a Cystadenoma of the Pancreas. Arch Surg. 1960;81(5):683-689. doi:10.1001/archsurg.1960.01300050005002.

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