In recent years with the larger number of patients examined at the Lahey Clinic who require secondary procedures on the biliary tract, we have encountered amputation neuromas with increasing frequency. The cases of amputation neuromas found between 1950 and 1955 were reviewed to determine whether anything could be learned of their relationship to the patients' symptoms or their possible influence on the function of the biliary tract, or both.
The first reported neuroma of the biliary tract, reported by Husseinoff6 in 1928, was located at the cystic duct stump. Similar findings were described by Shapiro and Lifvendahl8 in 1931. In both instances the neuromas were postmortem findings.The first neuroma of the bile ducts described in a clinical patient was reported by Comfort and Walters4 in 1931. It was associated with biliary obstruction. The next report was published by Cieslak and Stout3 in 1946; they