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Effect of Endocardial Incisions on Myocardial Blood Flow

Arch Surg. 1963;87(3):424-427. doi:10.1001/archsurg.1963.01310150060014.
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Surgical attempts to correct coronary insufficiency by increasing the blood flow to the myocardium have been directed toward supply from extracardiac sources or reconstruction of the coronary arteries.1 That a rich plexus of intramyocardial blood vessel anastomoses between the branches of the coronary arteries and the myocardial cavities exist is known.2,3 Cases have been reported where obstruction of both coronary arteries has apparently been compatible with life,'4 and it is speculated that part or all of the myocardial nourishment was supplied by intramyocardial vessels communicating with the heart cavities. It is known that these communications are the source of myocardial blood supply in certain lower animals. Experiments were devised in an attempt to increase the blood flow to the myocardium directly from the left ventricular cavity.

Method  Twenty-six mongrel dogs weighing between 8 and 15 kg were anesthetized with 25 mg/kg pentobarbital sodium (Nembutal) intravenously, and the


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