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ARTICLE |

Intentional Hemodilution

NAZIH ZUHDI, MD; JOHN CAREY, MD; JAMES CUTTER, MD; LLOYD RADER, MD; ALLEN GREER, MD
Arch Surg. 1963;87(4):554-559. doi:10.1001/archsurg.1963.01310160016004.
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After the publication of our early reports on hemodilution perfusion,1-4 Cooley et al5 suggested its usefulness for expediency in pulmonary embolectomy and recently used it routinely for total body bypass.6 DeWall and Lillehei7 and DeWall et al8 constructively elaborated on this subject.

Our comparative studies of two series of patients who had open-heart surgery with the aid of extracorporeal circulation using blood primes or 5% dextrose in water primes did not reveal the superiority of either method.9 The unfavorable theoretical and experimental attributes of blood primes did not materialize in our small series of patients. It is possible that the use of low priming volumes has obviated some of them, and it is conceivable that with larger series these disadvantages will become apparent. However, these studies demonstrated that 5% dextrose in water primes compare favorably with the conventional and traditional blood primes. This report

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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