Until the causes of venous thrombosis are more clearly defined, surgeons will continue to manage this problem by utilizing the most effective modes of therapy available in order to prevent death from pulmonary embolism and to obviate the crippling sequelae of the postphlebitic extremity. A series of investigations have previously been carried out in our laboratory to assess the effectiveness of fibrinolysin therapy for venous thrombosis, and the results were disappointing.1,6 The rapidity of clot propagation from a small focus was also investigated to test the logic of administering anticoagulant therapy.2 This present group of experiments was done to evaluate venous thrombectomy combined with systemic heparinization.
There has recently been a renewed enthusiasm for thrombectomy.5,7,8 The improved vascular techniques have made surgeons less timid about opening veins and closing them with fine silk sutures. The initial results are encouraging. The edema subsides rapidly, and the postphlebitic, chronically