We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Meaning of Five-Year Cure in Cancer of the Breast

Arch Surg. 1964;88(4):637-644. doi:10.1001/archsurg.1964.01310220127020.
Text Size: A A A
Published online


In recent years the rationale of the use of the classical radical mastectomy in the treatment of cancer of the breast has been questioned on several and often contradictory grounds: it has been judged both inadequate and excessively radical, and has also been pronounced essentially ineffective.1,12,16 On examining the evidence, it is not difficult to see that the statistical foundation of much of this criticism is unconvincing. All too often data unsuited for comparison are compared, significant factors bearing on results neglected, and the vagaries of the biological behavior of breast cancer ignored. The influence on statistical inference of the last named factor is of particular interest since it profoundly affects the significance of the socalled five-year cure, an almost universal measuring standard of therapeutic success. In studying the late (post-five-year) survival of our patients we have been impressed by the importance of this factor and by the need


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.