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Staphylococcal Sepsis and Patient's Nasal-Carrier State

Arch Surg. 1965;90(2):294-297. doi:10.1001/archsurg.1965.01320080118025.
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THE PROBLEM of infection with staphylococci during hospitalization is a threat to every patient admitted to a surgical service. Although there seems to have been a considerable decline in the rate of such infections since the late 1950's, every surgical ward continues to have instances of staphylococcal sepsis. As shown by Burke1 and Culbertson et al2 the source of the infecting organism and the reasons for clinical infection are undoubtedly multiple. The individual's own nares have been frequently incriminated as the source of the contaminating organism. Weinstein,3,4 Colbeck et al,5 Elek and Fleming,6 and Williams et al7 feel that this is an important source of such hospital acquired infection. Also it has been suggested by Weinstein,3,4 Williams et al,7 and Gillespie et al8 that elimination of staphylococci from the nasal passages of patients by antibiotic ointments or sprays might decrease the


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