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Assisted Circulation in Treatment of Experimental Heart Failure

PAUL R. ELLIS JR., MD; CHUL LEE, MD; SIDNEY H. WONG, MD; VICTOR C. DEL ROSARIO, MD; JOHN W. HYLAND, MD; GUY PRATOR, RN
Arch Surg. 1965;90(6):879-889. doi:10.1001/archsurg.1965.01320120081006.
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WITH THE development of low-priming volume oxygenators, assisted circulation has become available for emergency use. It has been suggested as treatment for a number of conditions including septicemic shock,1 cardiac arrest,2,3 pulmonary insufficiency,4 and congestive heart failure.5-12 Of these, emphasis has been placed on the use of circulatory support for the treatment of intractable heart failure after a myocardial infarction. The results, however, have been inconsistent and further evaluation of the use of assisted circulation in the treatment of heart failure is indicated.

In a previous publication,13 a technique was described for the production of experimental heart failure in animals by multiple coronary ligations. The resulting failure was found to be comparable to that occurring clinically following a myocardial infarction. The purpose of this study is to evaluate the effectiveness of various methods of assisted circulation in the treatment of experimental heart failure.

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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