September 1965, Vol 91, No. 3 >

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ARTICLE | September 1965

Extracorporeal Circulation in Puppies

JENS G. ROSENKRANTZ, MD; ROBERT MacMAHON, MD, FRCS; WARREN W. FROST, DVM; BRUCE C. PATON, MD, MRCP, FRCS; HENRY SWAN, MD

Arch Surg. 1965;91(3):513-515. doi:10.1001/archsurg.1965.01320150143028.

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DESPITE increasing success in intracardiac surgery in the young infant, mortality rates are still high. Among the difficulties inherent in such surgery, extracorporeal circulation in young, small individuals plays a prominent role. For this reason, experience with cardiopulmonary bypass in small animals is essential for successful intracardiac surgery in infants.

Several authors^1,7 have reported experiences with extracorporeal circulation in the puppy, and mortality rates have been high. The use of the dog for such experiments has been criticized, and an impression has been created that high mortality rates are to be expected.³

This paper reports initial experiences in this laboratory with extracorporeal circulation in young puppies and suggests that such procedures can be undertaken with reasonable expectation of success.

Material and Methods Mongrel puppies weighing 2.14 to 5.58 kg (4.7 to 12.3 lb) were anesthetized with intravenous pentobarbital (Nembutal), and positive pressure respiration was maintained with warmed, humidified

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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ROSENKRANTZ JG, MacMAHON R, FROST WW, PATON BC, SWAN H. Extracorporeal Circulation in Puppies. Arch Surg. 1965;91(3):513-515. doi:10.1001/archsurg.1965.01320150143028.

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