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Obstructive Pathophysiologic Changes in Retroperitoneal Fibrosis

Arch Surg. 1966;92(5):695-698. doi:10.1001/archsurg.1966.01320230043007.
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THE DIAGNOSIS of idiopathic retroperitoneal fibrosis as described first in the English literature by Ormond in 1948 is being made with increasing frequency.1 As physicians become more aware of this clinical syndrome and its symptom complex, the diagnosis will also be made earlier in the course of the disease. At the present time, over 100 cases have been reported in various journals.

The following case is presented not only as an example of idiopathic retroperitoneal fibrosis, but also as an illustration of the phenomenon of diuresis following the relief of urinary tract obstruction. This diuresis has occurred most commonly following relief of vesical neck obstruction.2-4 The importance of early recognition and proper management of the rapidly changing and shifting body constituents has been stressed repeatedly, for it has been truly said that the fluid and electrolyte imbalance may represent a more immediate threat to life than the underlying


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