0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Heidenhain Pouch Bleeding Due to Oral Salicylates

GEORGE N. COOPER JR., MD; ROBERT C. MEADE, MD; EDWIN H. ELLISON, MD
Arch Surg. 1966;93(1):171-174. doi:10.1001/archsurg.1966.01330010173021.
Text Size: A A A
Published online

THERE have been many clinical and experimental observations demonstrating a causal relationship between gastrointestinal bleeding and the ingestion of salicylate compounds.1-7 Many people investigating this problem have shown an erosive effect of acetylsalicylic acid on the gastric mucosa. Gastroscopic observations,5-7 autopsy studies,8,9 and surgical specimens3 have shown direct evidence of mucosal irritation after aspirin ingestion.

There has been much discussion regarding the ability of salicylates to cause gastrointestinal bleeding other than by direct mucosal irritation.10-14 Clark and Adams,15 while studying the effect of oral aspirin administration on gastric acid using ennervated Cope pouches,16 noted concomitant bleeding in the pouches. The bleeding, however, was not quantitated. Cope pouches (Fig 1) are constructed so that they do not provide for immediate egress of gastric juice. They, therefore, must be aspirated frequently to avoid distention and complications thereof.

It was our purpose in this study to

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();