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Effect of Intestinal Reversal and Massive Resection on Gastric Secretion

Arnis B. Grundberg, MD; Alberto S. Lopez, MD; Lester R. Dragstedt II, MD
Arch Surg. 1967;94(3):326-329. doi:10.1001/archsurg.1967.01330090020005.
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INTESTINAL reversal has been used in humans to delay the passage of food and to increase absorption in conditions where a large portion of the intestine has been resected. Massive intestinal resection alone has been shown to increase gastric secretion of acid.1-5

It is the purpose of this paper to see what effect a reversed jejunal segment has on gastric secretion alone and in combination with 75% intestinal resection.

There are several reports in the literature that indicate that intestinal reversal may affect gastric secretion.6-8 Whether an increase or decrease would result is not clear. Hammer and associates6 have done complete duodenal reversal and have shown that gastrojejunal ulcers occur. He believed this to be secondary to prolonged gastric retention with antral stimulation. On another occasion Hammer et al7 showed that gastric emptying is prolonged by a 2-inch reversed duodenal segment. Therefore, gastric retention and


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