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Rupture of the Spleen Secondary to Actinomycosis

Richard L. Sperling, MD; Raul Heredia, MD; William J. Gillesby, MD; Bernhard Chomet, MD
Arch Surg. 1967;94(3):344-348. doi:10.1001/archsurg.1967.01330090038009.
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CASES of traumatic1,2 and spontaneous3,4 rupture of the pathological spleen are frequently encountered.5,6 Rupture of the spleen has been reported with acute7 and chronic8 pancreatitis, acute sepsis9,10 (typhoid fever, typhus), viral hepatitis,11 infectious mononucleosis,12 the parasites causing malaria,9 kala-azar,10 and echinococcosis; the spirochetal diseases of leptospirosis, syphilis, and yaws, in tuberculosis, in sarcoidosis,13 in Gaucher's disease,14 amyloidosis, in thrombocytopenic purpura, acute and chronic leukemia,15 erythroblastosis fetalis,16 in autohemolytic anemia,1 congestive splenomegaly,17 infarcts, splenic congenital anomalies, and also during labor.18,19

We were able to find only one proven case of spontaneous rupture of the spleen due to actinomycosis found at the Mayo Clinic.20 Harrison21 previously stated that actinomycosis is encountered in the spleen, however, a review of Harrison's references reveal a case produced by Actinobacillus22 and another produced by Actinomyces graminis


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