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The Surgical Treatment of Cavitary Pulmonary Coccidioidomycosis

Austin R. Grant, MD; Dermont W. Melick, MD
Arch Surg. 1967;94(4):559-566. doi:10.1001/archsurg.1967.01330100123018.
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SURGICAL therapy is a well recognized method in the treatment of pulmonary coccidioidomycosis. This paper is confined solely to the surgery of the cavitary phase of this disease wherein postoperative complications are high. In view of this universally recognized hazard, an outline of a combined medical-surgical approach to reduce complications to a minimum will be presented.

Mycology  Fungi are simple plants, a plane higher than bacteria, of which only a few can cause disease in man, animals, or other plants. The fungus depends on living organisms for food and, therefore, is either saprophytic or parasitic in nature. Coccidioides immitis exists in two distinct phases—the saprophytic in external nature and on laboratory media and the parasitic in human or animal tissue. In the parasitic phase C immitis appears as a round, doubly refractile, walled spherule in infected tissue. Its cytoplasm divides by cleavage to form endospores which are liberated by rupture


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