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Thrombosis of Axillary and Subclavian Veins

William W. Coon, MD; Park W. Willis III, MD
Arch Surg. 1967;94(5):657-663. doi:10.1001/archsurg.1967.01330110073010.
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THROMBOSIS of the axillary and subclavian veins is a rare entity. In the statistical compilation by Barker et al of thromboembolic disease seen at the Mayo Clinic,1 thrombosis of deep veins of the upper extremity represented only 1.7% of 1,260 cases. In a recent assessment by us of 2,400 episodes of deep venous thrombosis recognized over a 15-year interval, thrombosis of deep veins of the arm constituted 1.3% of the total. The largest single group of cases we have encountered in the medical literature is a series of 46 patients reported by Veal and Hussey in 19432; these individuals received no specific therapy.

During the course of summarizing the results of anticoagulant therapy of deep venous thrombosis at our institution, we were impressed with a prognosis more favorable than expected2,3 in 33 patients with deep venous thrombosis of the upper extremity who received anticoagulants for treatment of


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