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Mulitiple Phlebectasia

Melvin A. Shiffman, MD; Irving Rappaport, MD
Arch Surg. 1967;94(6):771-775. doi:10.1001/archsurg.1967.01330120025006.
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SINCE THE first description of the syndrome of multiple phlebectasia of the jejunum, oral mucosa, tongue ("caviar spots"), and scrotum (Fordyce lesion),1 ten more patients have been seen with manifestations of this disorder. The lesions appear most frequently after the age of 40 years and are generally associated with the aging process. Peptic ulcer or ulcer-like symptoms are a common occurrence.

In patients with gastrointestinal bleeding of undetermined etiology, phlebectasia may be one of the responsible lesions. Recognition of the mucocutaneous manifestations can aid in the diagnosis of this disorder.

Report of Cases 

Case 1.  —A 62-year-old man entered the hospital in December 1963 with recurrent carcinoma of the colon at the site of anastomosis of the ileum with the colon. He had an anterior resection of the sigmoid colon for carcinoma in April 1960 and resection of the ascending and transverse colon for a new carcinoma in July


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