0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Silicone Fluid in the Prevention of Intestinal Adhesions

Charles F. Frey, MD; Christian Thorpe, MD; Gerald Brody, MD
Arch Surg. 1967;95(2):253-256. doi:10.1001/archsurg.1967.01330140091021.
Text Size: A A A
Published online

POSTOPERATIVE intestinal adhesions are the most common cause of small-bowel obstruction in the United States. Therefore, their prevention is desirable. While this goal is evident, the means of preventing adhesions are not. Elimination of operative trauma to the bowel which initiates the development of intestinal adhesions is often impossible. Should the intestinal serosa be abraded at operation, an inflammatory reaction begins minutes after injury. Within hours a fibrin exudate forms. The exudate undergoes organization, and fibroplasia is apparent as early as three to four days after injury. Fibroblast proliferation and collagen deposition lead to fibrous adhesions within ten days of operation. Maturation of adhesions proceeds rapidly up to 35 days after injury.1,2

Drugs which prevent clotting and lyse clots, act as lubricants, reduce inflammation, and inhibit fibroplasia have been employed in attempts to prevent intestinal adhesions, eg, steroids, antihistamines, heparin, amniotic fluid, mineral oil, lubricating jelly, fibrinolysin, dimethylsulfoxide, dextran,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();