0
ARTICLE |

"In Vivo" Staining of the Parathyroid Glands and Pancreas

Richard J. Hurvitz, MD; James S. Hurvitz; Leon Morgenstern, MD
Arch Surg. 1967;95(2):274-277. doi:10.1001/archsurg.1967.01330140112025.
Text Size: A A A
Published online

IT HAS BEEN observed that when toluidine blue, a quinone-imine group histologic stain,1 is injected intravenously into dogs it preferentially concentrates in the parathyroid glands, panceas, and gastric corpus, imparting a distinct coloration to these organs.2

Presented in this paper is a study of the intravenous and oral use of this dye in a series of dogs. The results of this investigation and the possible clinical implications of this study will be discussed.

Methods and Materials  Twenty-two mongrel dogs were anesthetized with intravenously administered sodium pentobarbital (30 mg per Kg of body weight).Toluidine blue (Toluidine Blue O) was prepared as a 1% solution in normal saline. The solution was then filtered through filter paper and autoclaved at 105 C for ten minutes.In ten animals, the dye solution (10 mg/kg of body weight) was injected intravenously over a one-minute period. In ten animals, the dye solution (10

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();