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Article |

Chemotherapy for Tumors of Chest Wall and Base of Neck by Arterial Infusion

Loren J. Humphrey, MD; Benjamin F. Rush Jr., MD
Arch Surg. 1968;96(5):810-813. doi:10.1001/archsurg.1968.01330230118016.
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IN 1959, Sullivan et al1 introduced the method of cancer chemotherapy by arterial infusion. They described cannulation of the external carotid artery, via the superior thyroid artery, for chemotherapy of head and neck tumors. Balla et al2 administered drug through a catheter passed retrograde down the superficial temporal artery.

The scope of arterial infusion has been enlarged to include most areas of the body; for example, Freckman et al3 modified the method described by Newton4 for treating primary carcinoma of the lung. Since then, selective catheterization of the bronchial arteries has been used by several investigators.5-7

Several approaches have been used for infusion chemotherapy of the liver of the ambulatory patient.8,9 Inoperable pelvic tumors can be treated with drug by inserting a catheter in the hypogastric artery.10

The purpose of this article is to describe a technique for infusing tumors of the chest


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