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ARTICLE |

Combined Burn Therapy Utilizing Immediate Skin Allografts and 0.5% AgNO3

John F. Burke, MD; Conrado C. Bondoc, MD
Arch Surg. 1968;97(5):716-721. doi:10.1001/archsurg.1968.01340050056006.
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DURING the last few years, the use of several topically applied antibacterial substances has been shown to provide an approach to satisfactory control of burn wound sepsis. Clinical experience has shown, however, that even with successful control of surface infection, the overall status of the extensively burned patient remains precarious until skin coverage is accomplished. It appears that the metabolic demands inherent in maintenance of homeostasis and in repair of damaged tissue, if carried on over a long period of time, may approach a magnitude with which the host cannot cope. Therefore, the rate at which the burn wound is closed is a primary factor in the overall treatment of the burned patient.

In order to avoid long periods of stress produced by a large open burn wound, a number of attempts have been made to produce a suitable synthetic material which would provide a temporary skin substitute. Clinical success

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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