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Influence of Surgical Correction of Primary Hyperparathyroidism on Associated Hypertension

T. Madhavan, MD; Boy Frame, MD; Melvin A. Block, MD
Arch Surg. 1970;100(2):212-214. doi:10.1001/archsurg.1970.01340200100022.
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The association of hypertension with primary hyperparathyroidism has been recognized in approximately one third of patients.1-5 Although many factors and vagaries can be involved in the etiology of hypertension, our experience indicates that hypertension is relieved after surgical correction of hyperparathyroidism in some patients, regardless of whether or not renal impairment is also present.

Materials and Methods  From our experience with 80 patients for whom primary hyperparathyroidism was corrected surgically, the prevalence of hypertension, both preoperatively and postoperatively, and of renal impairment were evaluated. Hypertention was considered to be present when morning basal blood pressure recordings or the average of at least two casual blood pressure recordings exceeded 150 mm Hg systolic and 100 mm Hg diastolic. The biochemical criteria for renal functional impairment consisted of a level of serum creatinine greater than 1.4 mg/100 cc. The radiologic criteria for renal structural damage consisted of the presence of one


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