0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

Hemodynamic Changes, Treatment, and Prognosis in Clinical Shock

Robert F. Wilson, MD; Edward J. Sarver, MD; Joseph Rizzo, MD
Arch Surg. 1971;102(1):21-24. doi:10.1001/archsurg.1971.01350010023005.
Text Size: A A A
Published online

The relationship between cardiac output, total peripheral resistance index (TPRI) treatment, and prognosis was evaluated in 151 patients studied by the Shock Unit of the Detroit General Hospital. Although the hemodynamic values did not correlate with the severity of the shock and did not have a significant effect on the outcome of the patients, the drugs used and the response to treatment were critical. Drugs which maintained or increased any hemodynamic abnormality were detrimental. There was a significant increase in mortality when vasoconstrictor drugs were used in patients who had a low cardiac output (less than 2.5 liters/min/sq m) and were vasoconstricted (TPRI above 2,200 dyne-sec/cm5/sq m). Likewise, the use of vasodilators in septic patients, especially those with the highest cardiac outputs (above 3.5 liters/min/sq m) and most vasodilation (TPRI less than 1,300 dyne-sec/cm5/sq m), was also associated with a significantly increased mortality.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();