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July 1971, Vol 103, No. 1 >

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ARTICLE | July 1971

Candida Septicemia

Richard J. Williams, MD; James G. Chandler, MD; Marshall J. Orloff, MD
Arch Surg. 1971;103(1):8. doi:10.1001/archsurg.1971.01350070034006.
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The records, culture material, and autopsy data of 27 patients with Candida septicemia revealed that the overall mortality was 72%, attributed in part to their primary disease as well as to the adverse effects of the Candida sepsis. Twenty-five of the 27 patients received multiple blood transfusions within two weeks of their positive blood cultures. Twenty-five patients had indwelling central venous catheters at the time that their positive Candida blood cultures were drawn. All but one of the entire group received broad-spectrum antibiotics in the two-week period preceding their disseminated candidiasis. These features appeared to be significant predisposing factors and probably account for the increased incidence of Candida septicemia noted in this report.

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