Fifteen extracranial, solitary, neurogenous, resected neoplasms of the face and neck involved major nerves or nerve plexuses. There were ten female and five male patients, ranging in age from 5 to 65 years. The nerves involved were: vagus, four; cervical sympathetic plexus, three; brachial plexus, two; facial, two; trigeminal, one; spinoaccessory, one; hypoglossal, one; and cervical sensory plexus, one. No tumor recurred. One patient was lost to follow-up, and in another intrathecal and aural meningiomas persisted. Ten of the 15 experienced postoperative neurological signs, and in five persistence to the date of this report occurred. Because the majority of these neoplasms are benign, the nerve of origin should be preserved during resection.