Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

The Diagnosis of Deep Vein Thrombosis Using the 125I Fibrinogen Test

Vijay Kakkar, FRCSE, FRCS
Arch Surg. 1972;104(2):152-159. doi:10.1001/archsurg.1972.04180020032006.
Text Size: A A A
Published online


A simplified technique for detecting phlebothrombosis of the legs is using radioiodinated fibrinogen. In 88 patients, the accuracy of the test was 92%, as determined by concurrent phlebography. The test was also applied in 784 patients in various high risk groups, wherein the incidence of phlebothrombosis was as follows: 469 elective surgical patients, 27.8%; 50 patients with hip fractures, 54%; 42 patients undergoing prostatectomy, 23.8%; 100 obstetric patients, 3%; 92 women undergoing major gynecological surgery, 18.8%; and 31 patients with proven myocardial infarction, 19%. The method was also useful in 82 patients thought to have established phlebothrombosis by clinical criteria. Disadvantages of the test include its inability to detect phlebothrombosis in the upper femoral and iliac regions, the possible risk of serum hepatitis (no cases seen in over 800 patients studied), and the number of personnel required if a large number of patients are to be screened. Its advantages are simplicity, accuracy, portability, and lack of trauma.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.