We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Bacterial Colonization Profile With Tracheal Intubation and Mechanical Ventilation

Lester R. Bryant, MD, DSc; J. Kent Trinkle, MD; Kazi Mobin-Uddin, MD; Jeanne Baker, RN; Ward O. Griffen Jr., MD, PhD
Arch Surg. 1972;104(5):647-651. doi:10.1001/archsurg.1972.04180050023006.
Text Size: A A A
Published online


Serial tracheal cultures were made in 129 patients who required tracheal intubation for 48 hours or longer. Twenty-eight patients were managed with endotracheal tubes and 101 had tracheostomy. Mechanical ventilation was required by 113 patients. Tracheal cultures became positive for pathogenic bacteria or fungi in 115 patients, and species of Pseudomonas, Klebsiella, Candida, and Proteus predominated. Replacement of one pathogen by another occurred frequently, and 43% of the patients became colonized with two or more gram-negative organisms. Tracheobronchitis occurred in 31 patients; 47 had pneumonitis; and 28 developed colonization without evidence of respiratory infection. Antibiotic overuse often resulted in infection with resistant organisms. The data suggest greater effort in distinguishing colonization from respiratory infection, with preferential omission of systemic antibiotics for simple colonization or tracheobronchitis.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.