During the past decade, organ transplantation moved rapidly from the experimental laboratory to the clinic. Professor Calne, the editor of this new book, is one of the pioneers and leaders of this movement. First to use azathioprine in animals, he has continued to make notable contributions to organ transplantation.
The book is basically an introduction to clinical organ transplantation. Professor Calne wrote three of the chapters, one each on the surgical technique of liver and kidney transplantation, and the third on ethics, the law, and the future of transplantation.
The first portion is a general introduction to transplantation biology. For a book of this type and size, an excellent overview is provided of the immense amount of basic information available. The authors are to be congratulated for clear, concise, understandable, and fair presentations. Fundamental topics such as pathological findings on rejection, histocompatibility typing, mixed lymphocyte reactions, and organ preservations are