Pulsatile Pressure-Regulated Coronary Perfusion During Ventricular Fibrillation

Akio Wakabayashi, MD; Takuji Kubo, MD; Philip Gilman, MD; William F. Zuber, MD; John E. Connolly, MD
Arch Surg. 1972;105(1):36-41. doi:10.1001/archsurg.1972.04180070034006.
Text Size: A A A
Published online

Flow-regulated vs pressure-regulated and pulsatile vs nonpulsatile coronary perfusion in the fibrillating heart were studied in dogs. Conventional total cardiopulmonary bypass was employed and coronary perfusion was achieved via the aortic root. The coronary sinus and right and left ventricles were separately cannulated for drainage and blood sampling for the calculation of oxygen consumption and coronary vascular resistance. It was found that thebesian shunt flow fluctuated widely during coronary perfusion. When shunt flow increased suddenly, flowregulated coronary perfusion could not meet the flow requirements, resulting in inadequate perfusion, in contrast to pressureregulated perfusion.

With pulsatile coronary perfusion it was found that (1) fluctuation of thebesian shunt flow was less, and (2) myocardial oxygen consumption and coronary vascular resistance were more stable than with nonpulsatile coronary perfusion.


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.