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ARTICLE |

Regeneration of Liver and Kidney

Stuart M. Poticha, MD
Arch Surg. 1972;105(3):533. doi:10.1001/archsurg.1972.04180090128035.
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ABSTRACT

Compensatory growth in response to injury is a striking characteristic of both the liver and kidney. These vital organs, which together account for over half of the cardiac output, are so essential to life that they have evolved remarkable regeneration processes surpassed only by muscle and skin.

This new book describes in explicit detail the complex morphologic and biochemical changes which occur in both the liver and kidney in response to loss of tissue mass. The direct and concise presentation provides the clinician with a clear understanding of the mechanisms, similarities, and differences in the response of these two organs. Thus the rapid hyperplasia which occurs within the liver is sharply contrasted to the slower hypertrophy of existing nephrons, accounting for most of the increase in renal mass.

At the same time, descriptions of complicated processes such as DNA synthesis and replication, or changes in the cellular ultrastructure provide the

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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