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A Membrane Oxygenator for Ex Vivo Perfusion of Small Organs

Arch Surg. 1973;106(5):740-741. doi:10.1001/archsurg.1973.01350170100030.
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To the Editor.—Perfusion of small organs has been reported by several groups. If organ viability is to be maintained, oxygenation of the perfusate is required. In order to perfuse ex vivo with a limited volume of perfusate, 50 to 60 ml, at a flow rate of 40 to 70 ml/min, the following oxygenator was modified from a model previously reported from Peter Bent Brigham Hospital, Boston.1 This modification includes decreasing the length of the membrane tube and thus decreasing the volume of the priming solution. The degree of oxygenation is maintained despite the decrease in tube length by allowing the oxygen to flow about the entire diameter of the silastic membrane tube.

The Apparatus.—A dimethyl silicone tubular membrane, 1,219 meters long and .013 cm thick, is wrapped around a solid cylinder as a strut, with a netlike wall (Fig 1), thus allowing the maximum oxygen interface around the circumference


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