Gastric emptying of liquid test meals was evaluated in dogs following parietal cell vagotomy with and without Heineke-Mikulicz pyloroplasty. Citrate and citrate-fat serial test meals and bethanechol chloride and insulin injection were used to characterize the emptying prior to and under each condition of surgery. The citrate meal emptied more rapidly than the citrate-fat meal. Parietal cell vagotomy (PCV) did not significantly alter the gastric emptying of these meals. However, there was a tendency to initially enhance the emptying rate of the citrate-fat test meal. The addition of a pyloroplasty did not effect the emptying of either test meal. Use of both insulin and bethanechol enhanced the emptying of the citrate-fat test meal. These emptying rates were uneffected by PCV or by the addition of a pyloroplasty.