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Article |

A Quarter Century With Splenectomy Changing Concepts

Peter J. Fabri, MD; Earl N. Metz, MD; William V. Nick, MD; Robert M. Zollinger, MD
Arch Surg. 1974;108(4):569-575. doi:10.1001/archsurg.1974.01350280169028.
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Twenty-five years in surgery of the spleen is summarized in 1,944 patients who have been operated on for hypersplenism (48%), other splenic disease (9%), Hodgkin staging (4%), trauma (10%), and the increasing number with splenectomy incidental (29%) to gastrointestinal disease, hepatic disease, or transplantation. This experience focuses on changing trends in hematological indications including Hodgkin staging, leukemic reticuloendotheliosis, and myelofibrosis; current concepts in patient selection based on splenic sequestration; adjuncts to operative management, and the continuing challenge to prevent surgical complications and lower mortality.


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