Gangrene of the Feet in Diabetics

Henry T. G. Williams, MB, ChB, FRCS (Eng), FRCS (C), FACS; Kenneth J. Hutchinson, MD; Gordon D. Brown, MD
Arch Surg. 1974;108(4):609-611. doi:10.1001/archsurg.1974.01350280209035.
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Three etiological factors–ischemia, peripheral neuropathy, and infection–underlie the development of gangrene of the feet in diabetics. The emphasis on each factor varies from patient to patient. A clinical classification based on the temperature of the foot divides patients with gangrene of the feet into three groups that occur with equal frequency: (1) necrosis in a cold foot, (2) necrosis in a hot foot, and (3) necrosis in a warm foot. In the first group, a major amputation is the inevitable result. Local excision and preservation of part of the foot is possible in all patients in the second group. It is worth attempting a local excision in the third group, as healing will occur in half the cases.


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