To the Editor.—We agree with Prinz et al1 regarding the continued importance of adrenalectomy in the treatment of Cushing's disease and the particular necessity for careful longterm follow-up when radiation to the pituitary gland is used. We have had the opportunity to study a 33-year-old woman who was treated with the conventional radiation to the pituitary gland for Cushing's disease in 1968 at a major medical center. Unfortunately, the patient moved out of state and was unavailable for follow-up. She did seek consultation in her new locality and was told that she did not have evidence of Cushing's disease and furthermore probably never had had this disorder.
Report of a Case.—When we first studied this patient in 1976, she was already severely disabled by a painful right hip and walked with crutches. Results of physical examination showed obesity (height, 1.57 m; weight, 84.15 kg), facial rounding, plethora,