We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Radioimmunoreactive Serum Elastase Levels and Histologic Changes During Experimental Pancreatitis in Rats

Katsusuke Satake, MD; Young-Suk Chung, MD; Takayuki Yoshimoto, MD; Kaoru Umeyama, MD; Toshio Ohyama, MD; Kouichi Katayama, PhD
Arch Surg. 1982;117(6):777-780. doi:10.1001/archsurg.1982.01380300025007.
Text Size: A A A
Published online


• A radioimmunoassay system showed elastase levels of 128 to 232 ng/mL in normal rat serum. The average normal value was approximately 64-fold greater than the minimal detectable amount. No cross-immunoreactivity was found with human elastase 1, porcine elastase, and trypsin. The elastase and amylase levels in rat serum were measured during pancreatitis induced by trypsin (group 1) and normal saline solution (group 2). Within 15 minutes the serum elastase and amylase levels increased significantly and remained elevated. The serum elastase levels in group 1 were significantly higher than in group 2. Hemorrhagic pancreatitis was found in group 1 and edematous pancreatitis was found in group 2 five hours after induction of pancreatitis. Elastase levels in these tissues were significantly lower than those in normal tissue. The levels in ascitic fluid were higher than those found in serum.

(Arch Surg 1982;117:777-780


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.