We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

A Quality Control Analysis of Aminoglycoside Management

Edward J. Quebbeman, MD, PhD; Timothy R. Franson, MD; Julianne E. Whipple, RPh; Jay Bubrick, RPh; John T. Kolesari, RPh; Robert Thomson, RPh; Robert K. Ausman, MD; Robert E. Condon, MD
Arch Surg. 1985;120(9):1069-1071. doi:10.1001/archsurg.1985.01390330075016.
Text Size: A A A
Published online


• Aminoglycoside administration practices were evaluated in a teaching hospital using three study methods: a chart review of 40 randomly selected patients receiving aminoglycosides was conducted retrospectively; 93 health care personnel involved in ordering and administering aminoglycosides to patients were interviewed regarding their understanding of aminoglycoside utilization practices; and ten patients having serum peak and trough aminoglycoside determinations were closely monitored for accuracy of dose administration and obtaining blood specimens at appropriate times. The chart review showed that during 15 of 32 evaluable therapy courses no determinations of serum aminoglycoside concentration were obtained. The survey demonstrated that only 24% of the residents actually used the results of peak and trough determinations to adjust dosage regimens. Direct observation of health care personnel disclosed only two of ten instances in which doses were administered and serum concentration specimens obtained with no apparent problems. Most personnel in our hospital were unaware of these pervasive suboptimal or inconsistent practices associated with aminoglycoside administration and interpretation of laboratory results.

(Arch Surg 1985;120:1069-1071)


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.