Dakin's Solution in Wound Treatment

Arch Surg. 1988;123(12):1525-1526. doi:10.1001/archsurg.1988.01400360095020.
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To the Editor.—In their recent article, Kozol et al1 examined the effects of Dakin's solution on cells using a wound module and generalized from this to recommend that the use of Dakin's solution be abandoned in the clinical setting. For generations, thousands of surgeons have found Dakin's solution to be an extremely useful agent in the treatment of what Rudolph and Noe2 called "chronic problem wounds." These authors expound at some length on their enthusiasm for the advantages of Dakin's solution. Surgeons who care for pressure ulcers and similar problems have found Dakin's solution to be a safe, effective, minimally morbid, and very inexpensive pharmacologic adjunct. While normal saline solution and similar physiologically compatible solutions are preferable for mimicking the physiologic milieu that encourages healing, Dakin's solution is far superior where chemical débridement is indicated. Despite the great amount of clinical support that has accumulated over the


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