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Article |

Conservative Surgery With Radiation Therapy in Clinical Stage I and II Breast Cancer Results of a 20-Year Experience

Bruce G. Haffty, MD; Neal B. Goldberg, MD; Marie Rose, PA; Barbara Heil, PA; Diana Fischer, PhD; Malcolm Beinfield, MD; Charles McKhann, MD; Joseph B. Weissberg, MD
Arch Surg. 1989;124(11):1266-1270. doi:10.1001/archsurg.1989.01410110020003.
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• Conservative surgery and radiation therapy have been increasingly utilized at Yale–New Haven (Conn) Hospital since the 1960s. This analysis represents our experience from 1962 to 1982, with a total of 281 patients having a minimum assessable follow-up of five years and a median follow-up of 7.4 years. Five- and ten-year actuarial survivals were 83% and 67%, respectively. The actuarial breast recurrence-free rate was 91% at five years and 80% at ten years. Of 31 patients having recurrences in the breast alone, the actuarial five-year survival following recurrence was 48%. Twenty-eight (90%) of these 31 recurrences were salvageable with mastectomy or repeated wedge resection. Patients experiencing an early breast recurrence (less than three years) following initial treatment had a poorer prognosis than patients having recurrences later.

(Arch Surg 1989;124:1266-1270)


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