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Cytologic Diagnosis of Aspergillosis in Cardiac Transplantation

Timothy H. McCalmont, MD; Jan F. Silverman, MD; Kim R. Geisinger, MD
Arch Surg. 1991;126(3):394-396. doi:10.1001/archsurg.1991.01410270144022.
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• Fine-needle aspiration of the lung is now widely utilized to diagnose pulmonary neoplasms, but often serologic techniques or open-lung biopsy is relied on for the diagnosis of infectious pulmonary processes. We report a series of four patients in whom the fine-needle aspiration technique was used to make the rapid cytologic diagnosis of pulmonary aspergillosis. Culture confirmation was also obtained on the aspirated material. A discussion of the available techniques for the laboratory diagnosis of pulmonary aspergillosis is presented and the advantages of fine-needle aspiration cytology are stressed. Our favorable results support expanded use of fine-needle aspiration cytology in the evaluation of lung nodules appearing in immunosuppressed populations.

(Arch Surg. 1991;126:394-396)

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