The editors of the American Medical Association's scientific publications (JAMA and the 10 specialty journals) in a consentaneous decision chose the topic of molecular medicine for their 1993 concurrent theme issue. The theme issue precedent was initiated in 1991 when the chosen topic was "Caring for the Uninsured and Underinsured" (Arch Surg, May 1991), and in 1992, the topic of "Violence" (Arch Surg, June 1992) was addressed. 1993 marks the 40th anniversary of the analysis of the DNA double helix structure by J. D. Watson and F. H. C. Crick. The Archives of Surgery is pleased to join with other editors in devoting the November 1993 issue of the Archives to biomolecular medicine.
The landmark publications appearing in Nature in 19532,3 set in motion a revolution in research that has rapidly enlarged our knowledge base and opened new vistas of research and our understanding of disease processes. The brevity