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Article |

Histologic Changes After Stenting of the Pancreatic Duct

Carlos Alvarez, MD; Marie Robert, MD; Stuart Sherman, MD; Howard A. Reber, MD
Arch Surg. 1994;129(7):765-768. doi:10.1001/archsurg.1994.01420310097018.
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The placement of stents has been proposed as a possible modality to treat pancreatic diseases. Ductal changes observed on endoscopic retrograde cholangiopancreatography during stenting are believed to be reversible when the stents are removed. We describe a patient with normal anatomy on baseline pancreatograms who underwent endoscopic sphincterotomy, followed by stent placement for 9 months. Symptoms progressed, leading to a pancreaticoduodenectomy. Histologic evaluation of the head of the pancreas revealed more extensive inflammatory changes in the duct and parenchyma drained by the stent. This suggests that stent-induced changes noted on pancreatography correspond to parenchymal changes that may be severe and irreversible.

(Arch Surg. 1994;129:765-768)


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