We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Liver Resection for Hepatocellular Carcinoma in the Elderly

Kenji Takenaka, MD; Mitsuo Shimada, MD; Hidefumi Higashi, MD; Eisuke Adachi, MD; Takashi Nishizaki, MD; Katsuhiko Yanaga, MD; Takashi Matsumata, MD; Toshihiko Ikeda, MD; Keizo Sugimachi, MD
Arch Surg. 1994;129(8):846-850. doi:10.1001/archsurg.1994.01420320072014.
Text Size: A A A
Published online


Objective:  To estimate the effectiveness of hepatic resection on hepatocellular carcinoma (HCC) in the elderly.

Design:  Comparison with younger patients.

Setting:  A municipal hospital and a large university hospital in Japan.

Patients:  The study included 39 patients (age ≥70 years [the elderly group]) and 229 patients (age <70 years [the younger group]) who underwent hepatic resection from April 1985 to March 1993. The preoperative clinical features (Child's classification, association of cirrhosis and liver functions) were comparable between two groups. The positive rate for hepatitis C virus antibody was higher in the elderly group (88% vs 59%; P=.016).

Main Outcome Measures:  Morbidity and survival following operation and the pathological features of HCC.

Results:  The incidence of postoperative hepatic failure was higher in the elderly group (10% vs 2%; P=.018). However, the incidence of operative death in the elderly group (5% vs 1%) as well as the incidence of other postoperative complications and rates of long-term survival (75.9% vs 51.6% at 5 years) and disease-free survival (30.4% vs 31.0% at 5 years) were similar to those in the younger group. The pathological features of HCC were identical between the two groups.

Conclusion:  The outcome of surgical treatment of HCC in the elderly group was satisfactory when compared with that in the younger group.(Arch Surg. 1994;129:846-850)


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.