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Article |

Preemptive Analgesia in Patients Undergoing Appendectomy

Clifford Y. Ko, MD; Jesse E. Thompson Jr, MD; Amelia Alcantara, CRNA, MS; Darryl Hiyama, MD
Arch Surg. 1997;132(8):874-878. doi:10.1001/archsurg.1997.01430320076012.
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Objective:  To evaluate the use of preemptive analgesia in patients who were undergoing an operation for acute appendicitis.

Design:  Double-blind, randomized control trial.

Setting:  Public hospital.

Patients:  Patients who presented with presumed appendicitis.

Intervention:  Patients received 1 of the following treatments: group 1, preemptive analgesia with a combination of lidocaine hydrochloride and bupivacaine hydrochloride; group 2, preemptive analgesia with saline solution; or group 3, nothing.

Main Outcome Measures:  The Wong-Baker FACES Pain Rating Scale, analgesic requirements, number of analgesic doses required, and length of hospital stay.

Results:  No differences were noted in postoperative pain, the total number of analgesic doses per day, the quantity of narcotic medication administered, and the length of hospital stay.

Conclusions:  Compared with healthy control subjects, preemptive analgesia did not reduce postoperative pain, reduce analgesic requirements, or shorten the length of hospital stay in patients who underwent an appendectomy. Preemptive analgesia may be applicable only for patients without preoperative pain.Arch Surg. 1997;132:874-878


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