Nissen fundoplication decreases the use of antireflux medications.
Retrospective cohort study using discharge abstract data and pharmacy data.
Twelve regional Kaiser Permanente hospitals in southern California.
Three hundred forty-two patients underwent Nissen fundoplication.
Main Outcome Measure
Use of antireflux medications.
The number of patients requiring antireflux medications decreased from 233 patients (68.1%) before Nissen fundoplication to 197 (57.6%) after Nissen fundoplication. Of the 233 patients, 176 (75.6%) were restarted on antireflux medications within 1 year after Nissen fundoplication. Use of antireflux medication decreased in neurologically healthy patients but was unchanged in neurologically impaired children.
Use of antireflux medication decreased after Nissen fundoplication. Neurologically healthy children showed the biggest decrease in antireflux medication use after Nissen fundoplication.