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We read with interest the article by Robson et al,1 who developed trajectories to evaluate wound healing in patients with diabetic foot ulcers. The authors point out that measuring outcome in wound healing is difficult because of the absence of objective criteria to evaluate the healing process before total wound healing has taken place. Particularly in slowly healing wounds, this is recognized as a major problem in evaluating outcome because 100% wound closure cannot always be achieved within an acceptable period of time in all study patients.
For several years we have investigated the beneficial effects of polarized light on burn wounds that are difficult to heal.2 At this time, progression in wound healing is measured by laser Doppler imaging. This technique uses the Doppler effect to assess blood movement in the microvasculature of tissue. It monitors perfusion throughout the dermis and just beyond.3 High flux indicates a favorable prognosis for wound healing, whereas low flux predicts difficult or impossible spontaneous wound closure. In this way, at the time of study entry, patients can be divided into groups according to depth and surface of injury.
We believe that the pathophysiology and type of injuries associated with burns are not comparable with those of diabetic ulcers. Nevertheless, we are convinced that laser Doppler imaging can provide objective information on wound-healing progress in burns. Tissue perfusion may indicate progression or worsening of the healing status in every wound.
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal
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