RT Journal
A1 Barie PS
T1 ADenoviral vector infection of the pancreas—reply
JF Archives of Surgery
JO Archives of Surgery
YR 1998
FD March 1
VO 133
IS 3
SP 336
OP 337
DO 
UL http://dx.doi.org/
AB 
Gastric tonometry has been championed as a method for indirect assessment of regional perfusion, which is an area where advanced methods are urgently needed. Assessment of splanchnic perfusion has been a desired goal because of the known sensitivity of the splanchnic vascular bed to hypoperfusion associated with systemic shock and low cardiac output states. Indeed, splanchnic hypoperfusion has been postulated to be central to the pathogenesis of the multiple organ dysfunction syndrome, which remains the leading cause of death in the surgical intensive care unit.1 For example, "stress-related" gastric mucosal injury has been associated experimentally with a local ischemia-reperfusion injury and generation of reactive oxygen species.2