RT Journal A1 Cilley RE T1 IMproved survival in congenital diaphragmatic hernia with evolving therapeutic strategies—invited commentary JF Archives of Surgery JO Archives of Surgery YR 1998 FD May 1 VO 133 IS 5 SP 503 OP 503 DO 10.1001/archsurg.133.5.503 UL http://dx.doi.org/10.1001/archsurg.133.5.503 AB The implications of these observations leave a number of unanswered questions. These include: (1) Should CDH repair ever be performed at institutions where ECMO is not available? (2) Should all women known to be carrying a fetus with CDH plan to deliver in such centers? (3) Is it ever appropriate to operate immediately after birth on an infant with CDH? (4) May repair be delayed for longer periods than the 2 to 5 days that the authors suggest? (5) In high-risk patients who require immediate ECMO support, must CDH repair always be performed while the patient is receiving ECMO as the authors have practiced, or may CDH repair be delayed until ECMO treatment has been completed? (6) Are there any infants with CDH who are "too sick" to survive and for whom no therapy should be offered? (7) With reports of improved survival rates using conventional postnatal therapy, what, if any, is the role of fetal therapy in the treatment of CDH?