RT Journal
A1 Tiwari A, Cheng K, Button M, Myint F, Hamilton G
T1 DIfferential diagnosis, investigation, and current treatment of lower limb lymphedema
JF Archives of Surgery
JO Archives of Surgery
YR 2003
FD February 1
VO 138
IS 2
SP 152
OP 161
DO 10.1001/archsurg.138.2.152
UL http://dx.doi.org/10.1001/archsurg.138.2.152
AB Hypothesis 
    The causes and management of lower limb lymphedema in the Western population are different from those in the developing world.Objective 
    To look at the differential diagnosis, methods of investigation, and available treatments for lower limb lymphedema in the West.Data Source 
    A PubMed search was conducted for the years 1980-2002 with the keyword "lymphedema." English language and human subject abstracts only were analyzed, and only those articles dealing with lower limb lymphedema were further reviewed. Other articles were extracted from cross-referencing.Results 
    Four hundred twenty-five review articles pertaining to lymphedema were initially examined. This review summarizes the findings of relevant articles along with our own practice regarding the management of lymphedema.Conclusions 
    The common differential diagnosis in Western patients with lower limb swelling is secondary lymphedema, venous disease, lipedema, and adverse reaction to ipsilateral limb surgery. Lymphedema can be confirmed by a lymphoscintigram, computed tomography, magnetic resonance imaging, or ultrasound. The lymphatic anatomy is demonstrated with lymphoscintigraphy, which is particularly indicated if surgical intervention is being considered. The treatment of choice for lymphedema is multidisciplinary. In the first instance, combined physical therapy should be commenced (complete decongestive therapy), with surgery reserved for a small number of cases.